50-198-2774
GAS2 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2774-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2774 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
GAS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GAS2
Gene Alias
GAS 2; GAS2; Gas-2; growth arrest specific 2; growth arrest-specific 2; Growth arrest-specific protein 2; RGD1563167
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2620
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
O43903
Gene Symbols
GAS2
Immunogen
KLH conjugated synthetic peptide derived from human GAS2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Gas2 is a 313 amino acid protein encoded by the human gene GAS2
- Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases
- Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis
- The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells
- Gas2 is believed to also be involved in the membrane ruffling process
- During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues
- Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts
- Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles
- Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney.