CKIP-1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2791-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2791 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
CKIP-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLEKHO1
Gene Alias
2810052M02Rik; BOS_2962; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CK2 interacting protein 1; CK2 interacting protein 1; HQ0024c protein; CK2-interacting protein 1; CKIP1; CKIP-1; HQ0024c; HQ0024c protein; JBP; Jun zipper-associated 2; Jza2; JZA-20; LOC100152184; OC120; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; pleckstrin homology domain containing O1; pleckstrin homology domain containing, family O member 1; Pleckstrin homology domain-containing family O member 1; pleckstrin homology domain-containing family O member 1-like; PLEKHO1; RGD1311487; RP11-458I7.3; TNF intracellular domain-interacting protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
51177
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q53GL0
Gene Symbols
PLEKHO1
Immunogen
KLH conjugated synthetic peptide derived from human CKIP-1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex
- CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha′, and is thought to play a role in targeting CK2alpha to a particular cellular location
- CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton
- CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM
- CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.