50-198-2795

Gcn1l1 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-2795-Each-of-1 In Stock ₹ 38,381.25

50-198-2795 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

Gcn1l1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GCN1

Gene Alias

4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; GCN1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; HsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; Translational activator GCN1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10985

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q92616

Gene Symbols

GCN1

Immunogen

KLH conjugated synthetic peptide derived from human Gcn1l1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Thioredoxin-interacting protein belongs to the arrestin family
  • It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability
  • It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest
  • It is required for the maturation of natural killer cells
  • Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1beta.