50-198-2946
GPR26 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2946-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2946 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
GPR26
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Gpr26
Gene Alias
9630036A11Rik; A730021D22; DKFZp761H2121; FLJ33774; G protein-coupled receptor 26; Gpr26; G-protein coupled receptor 26; MGC138216; probable G-protein coupled receptor 26
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2849
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q8NDV2
Gene Symbols
Gpr26
Immunogen
KLH conjugated synthetic peptide derived from human G protein-coupled receptor 26.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value
- GPR26 is a brain-specific orphan GPCR with a significant level of constitutive activity
- Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP
- In the CNS, the highest GPR26 expression is in the amygdala, hippocampus and thalamus
- Weak expression is detected in testis
- GPR26 is down-regulated in glioblastoma
- Depletion of GPR26 has been shown to increase fat storage in C
- elegans, whereas GPR26 deficiency in the hypothalamus is associated with high genetic susceptibility to the onset of obesity in mice
- GPR26 deficiency also causes metabolic complications commonly associated with obesity, including glucose intolerance, hyperinsulinemia, and dyslipidemia.