PER1 protein Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-4656-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-4656 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
PER1 protein
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PER1
Gene Alias
Circadian clock protein PERIOD 1; Circadian pacemaker protein Rigui; hPER; hPER1; KIAA0482; mPER1; m-rigui; PER; Per1; per1 {ECO:0000312; period 1; period circadian clock 1; Period circadian protein homolog 1; period homolog 1; Period, drosophila, homolog of; RGD:727863}; RIGUI; rPER1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5187
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
O15534
Gene Symbols
PER1
Immunogen
KLH conjugated synthetic peptide derived from human PER1 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Circadian rhythmicity is a basic property of phylogenetically diverse organisms which range from animals and plants, to fungi
- Regulation of endogenous biological clocks is regulated at the genetic level by a protein-mediated, autoregulatory feed-back loop
- In mammals, several genes that encode members of the basic helix-loop helix (bHLH) PAS (PER-ARNT-SIM) transcription factor family have been shown to play a significant role in regulating circadian oscillations
- Transactivation of CLOCK-induced genes is mediated via an E box enhancer (CACGTG) found upstream of target genes
- CLOCK-ARNT3 heterodimers bind to E box regulatory elements and stimulate gene transcription
- CLOCK has been shown to transactivate the mammalian homolog of Drosophila per
- PER, in concert with the product of the mammalian timeless gene (TIM), negatively regulates its own transcription by blocking the activity of the CLOCK-BMAL1 transactivation complex.