Phospho-DARPP32 (Thr34) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5154-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5154 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-DARPP32 (Thr34)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ppp1r1b
Gene Alias
AU040756; DARPP32; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine and cAMP-regulated neuronal phosphoprotein 32; dopamine- and cAMP-regulated phosphoprotein DARPP-32; FLJ20940; IPPD; neuronal phosphoprotein DARPP-32; OTTHUMP00000164275; OTTHUMP00000164276; PPP1R1B; PPR1B; protein pho; protein phosphatase 1 regulatory inhibitor subunit 1B; Protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1, regulatory (inhibitor) subunit 1B
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
84152
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q9UD71
Gene Symbols
Ppp1r1b
Immunogen
KLH conjugated synthetic phosphopeptide derived from human DARPP32 around the phosphorylation site of Thr34.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DARPP-32 is a dopamine (DA) and AMP-regugated ˜32 kDa phosphoprotein that is associated with dopaminoceptive neurons
- The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34
- In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA
- Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission
- In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac™.