Phospho-PAK1/PAK2/PAK3 (Thr423, Thr402, Thr421) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5303-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-PAK1/PAK2/PAK3 (Thr423, Thr402, Thr421)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pak1
Gene Alias
5330420P17Rik; A130002K10Rik; activated protein kinase alpha; ADRB2; adriamycin resistance-associated; AI836325; Alpha-PAK; ARA; AW045634; Beta-PAK; bPAK; CDC42/RAC effector kinase PAK-A; CDC42/RAC effector kinase PAK-B; CDKN1A; C-t-PAK2; D16Ertd269e; EC 2.7.11.1; Gamma-PAK; hPAK3; kinase PAK1; mKIAA4182; MRX30; MRX47; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p27; p34; p58; p65-PAK; p68-PAK; PAK 1; PAK alpha; PAK beta; PAK gamma; Pak1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; Pak3; Pak-3; PAK3beta; PAK65; Pak65alpha; Pak65beta; Paka; PAKalpha; Pakb; PAKgamma; Protein kinase MUK2; S6/H4 kinase; Serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; Serine/threonine-protein kinase PAK 3; STE20 homolog, yeast; Stk4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18479, 18481, 224105, 29431, 29432, 29433, 5058, 5062, 5063
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
O75914, O88643, P35465, Q13153, Q13177, Q61036, Q62829, Q64303, Q8CIN4
Gene Symbols
Pak1, PAK2, PAK3
Immunogen
KLH conjugated synthetic phosphopeptide derived from human PAK1 around the phosphorylation site of Thr423.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In mammals, there are several identified isoforms of p21-Activated Protein Kinases or PAKs: alpha-PAK (also known as PAK-1) and beta-PAK (also known as PAK-3) are mostly brain-specific, while gamma-PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003)
- Mutations of the gene coding for PAK-3 are associated wit X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004)
- PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003; Walter et al., 1998)
- Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).