Phospho-A Raf (Tyr301, Tyr302) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5388-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5388 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-A Raf (Tyr301, Tyr302)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARAF
Gene Alias
1200013E08Rik; ARAF; A-raf; A-Raf proto-oncogene serine/threonine-protein kinase; A-Raf proto-oncogene, serine/threonine kinase; Araf1; A-raf-1; AW495444; Oncogene ARAF1; PKS; PKS2; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks; Raf related protein; RAFA1; raf-related oncogene; Ras-binding protein; Ras-binding protein DA-Raf; RP1-230G1.1; Serine/threonine-protein kinase A-Raf; v-raf murine sarcoma 3611 viral oncogene homolog; v-raf murine sarcoma 3611 viral oncogene homolog 1; v-raf murine sarcoma 3611 viral oncogene-like protein; v-raf oncogene homolog 1 (murine sarcoma 3611 virus)
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11836, 369, 64363
Content And Storage
-20°C
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P04627, P10398, P14056
Gene Symbols
ARAF
Immunogen
KLH conjugated synstic phosphopeptide derived from human A Raf around the phosphorylation site of Tyr301/302 [G (p-Y) (p-Y)WE].
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways
- These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1
- Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity
- It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus
- The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain
- A-Raf, a second member of the Raf gene family of serine/ threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere
- Expression of A-Raf is found at highest levels in urogenital tissues and kidney and at lowest level in brain tissue.