50-198-5410

Phospho-Tie2 (Ser1119) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5410-Each-of-1 In Stock ₹ 38,381.25

50-198-5410 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

Phospho-Tie2 (Ser1119)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TEK

Gene Alias

AA517024; Angiopoietin-1 receptor; CD202b; CD202b antigen; EC 2.7.10; EC 2.7.10.1; Endothelial tyrosine kinase; endothelial-specific receptor tyrosine kinase; endothelium-specific receptor tyrosine kinase 2; endothelium-specific receptor tyrosine kinase Tie-2; hTIE2; Hyk; LOC100356675; mTIE2; p140 TEK; STK1; Tek; TEK receptor tyrosine kinase; TEK tyrosine kinase, endothelial; TEKT1; Tektin-1; tie2; Tie-2; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor Tie-2; VMCM; VMCM1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7010

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q02763

Gene Symbols

TEK

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Tie2 around the phosphorylation site of Ser1119.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2
  • This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family
  • The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats
  • The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development
  • Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP
  • HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.