G protein beta 1/GNB1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5773-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5773 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
G protein beta 1/GNB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GNB1
Gene Alias
AA409223; beta subunit, signal-transducing proteins GS/GI; BOS_15860; C77571; G protein subunit beta 1; GNB1; Gnb-1; gnb1 protein; gnb1a; guanine nucleotide binding protein (G protein), beta 1; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide binding protein (G protein), beta polypeptide 1a; guanine nucleotide binding protein, beta 1; Guanine nucleotide-binding protein beta 1; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; guanine nucleotide-binding protein, beta-1 subunit; MRD42; T beta; testicular tissue protein Li 72; Transducin beta chain 1; wu:fb50b09; wu:fj94h04
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2782
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P62873
Gene Symbols
GNB1
Immunogen
KLH conjugated synthetic peptide derived from human G protein beta 1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain
- The process of converting light into an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina
- Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active
- In the active state, rhodopsin activates transducin, a GTP binding protein
- Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE)
- The decrease of intracellular cGMP concentration causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission
- Rhodopsin activity is believed to be shut off by phosphorylation followed by binding of the soluble protein, arrestin
- Transducin, once activated by rhodopsin, promotes the hydrolysis of cGMP by PDE
- The subunit composition of transducin differs between different photoreceptor cells
- Rod transducin consists of rod transducin alpha (Tr alpha), T beta, and T gamma
- Cone transducin is composed of cone transducin alpha (Tc alpha), T beta and T gamma
- Differential transducin subunit composition of transducin is believed to be responsible for the different light sensitivities between photoreceptive cells.