TBLR1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5987-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5987 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
TBLR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TBL1XR1
Gene Alias
8030499H02Rik; A630076E03Rik; AW539987; C21; C230089I12Rik; DC42; F-box-like/WD repeat protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; FLJ12894; IRA1; MRD41; nuclear receptor co-repressor/HDAC3 complex subunit; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; RGD1560053; TBL1-related protein 1; Tbl1xr1; Tblr1; transducin (beta)-like 1 X-linked receptor 1; transducin (beta)-like 1X-linked receptor 1; Transducin beta-like 1X-related protein 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
79718
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q9BZK7
Gene Symbols
TBL1XR1
Immunogen
KLH conjugated synthetic peptide derived from human TBLR1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells
- The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) play a role in diverse transcriptional repression pathways
- N-CoR and SMRT each exist in large protein complexes, and are thought to mediate repression, at least in part, by their ability to recruit histone deacetylases to generate repressive chromatin
- HDAC3 is the main HDAC that associates with N-CoR and SMRT complexes, and its presence is thought to be essential for repression
- TBLR1 is a WD-40 repeat protein that also associates with N-CoR and SMRT complexes
- Although TBLR1 is thought to be a core component of both the N-CoR and SMRT complexes, its role in these complexes remains to be elucidated.