50-198-7977
CHMP4B+CHMP4C Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-7977-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-7977 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
CHMP4B+CHMP4C
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CHMP4B
Gene Symbols
CHMP4B, CHMP4C
Immunogen
KLH conjugated synthetic peptide derived from human CHMP4B/CHMP4C.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q569C1, Q96CF2, Q9D7F7, Q9D8B3, Q9H444
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100359642, 128866, 361916, 66371, 75608, 92421
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs
- MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids
- The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes
- ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released
- The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).