50-198-8671

GPR120 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-8671-Each-of-1 In Stock ₹ 38,381.25

50-198-8671 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

GPR120

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FFAR4

Gene Alias

AI552415; BMIQ10; FFAR4; Free fatty acid receptor 4; G protein-coupled receptor 120; GPCR120; Gpr120; GPR129; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01; GT01; KPG_013; O3far1; Omega-3 fatty acid receptor 1; PGR4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

338557

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q5NUL3

Gene Symbols

FFAR4

Immunogen

KLH conjugated synthetic peptide derived from human G protein coupled receptor 120.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • An EST for GPR120 has been isolated from a human colon cancer library
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This ''turn-off'' activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.