50-198-8694
G1switch 2 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-8694-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-8694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
G1switch 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
G0s2
Gene Alias
AI255151; AV006465; G0/G1 switch 2; G0/G1 switch gene 2; G0/G1 switch protein 2; G0/G1 switch regulatory protein 2; G0/G1switch 2; G0S2; G0S2-like protein; Putative lymphocyte G0/G1 switch gene; putative lymphocyte G0/G1 switch protein 2; RP1-28O10.2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
50486
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P27469
Gene Symbols
G0s2
Immunogen
KLH conjugated synthetic peptide derived from human G0/G1 switch protein 2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description The G(0)-G(1) switch gene 2 (G0S2) codes for a mitochondrial protein that is important in apoptosis, lipolysis, and triacylglycerol hydrolysis
- In adipocytes, G0S2 binds to adipose triglyceride lipase and decreases the breakdown of lipid droplets
- In Crohn′s colitis, the presence of G0S2 is increased in correlation to the amount of non-converted lipid in waste
- In squamous lung cancer, mutations in the G0S2 gene are common
- In breast cancer, epigenetic silencing of G0S2 occurs, and normal apoptotic regulation of aberrant cells is negatively impacted
- However, when G0S2 is not epigenetically modified, it is the best mediator of the Bcl-2/Bax heterodimer, resulting in apoptosis of cancerous cells.