50-198-8973

CENPO Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-8973-Each-of-1 In Stock ₹ 38,381.25

50-198-8973 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

CENPO

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CENPO

Gene Alias

2810429O05Rik; 8430427C03Rik; Cenpo; CENP-O; Centromere protein O; centromeric protein O; D12Ertd482e; ICEN36; ICEN-36; Interphase centromere complex protein 36; MCM21R

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

79172

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9BU64

Gene Symbols

CENPO

Immunogen

KLH conjugated synthetic peptide derived from human CENPO.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle
  • The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis
  • One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar
  • These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage
  • CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.