50-199-0031
CDK4Rabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-0031-Each-of-1 | In Stock | ₹ 52,930.08 |
50-199-0031 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
CDK4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdk4
Gene Alias
BOS_5594; CDK4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; Cyclin-dependent kinase 4; MGC14458; p34/cdk4; PSK-J3; serine/threonine kinase
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
85 mg/mL
Formulation
Antibody with 0.01% sodium azide; pH
Gene Accession No.
P11802, P30285, P35426
Gene Symbols
Cdk4
Immunogen
CDK4 (p34) peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Regulatory Status
RUO
Gene ID (Entrez)
1019, 12567, 94201
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Antiserum will specifically react with a 34 kDa cdk4 (p34) protein from human, rat and mouse tissue
- No reaction was observed against other related cyclin dependent kinases
- Cross reactivity with cdk4 (p34) from other species has not been determined
- CDK4 is a member of the Ser/Thr protein kinase family
- This protein is highly similar to the gene products of S
- cerevisiae cdc28 and S
- pombe cdc2
- It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression
- The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a)
- This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)
- Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers
- Multiple polyadenylation sites of the gene have been reported.