alpha-2-Macroglobulin Polyclonal Antibody, Biotin, Rockland™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-0401-Each-of-1 | In Stock | ₹ 50,829.68 |
50-199-0401 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,829.68
GST (18%): ₹ 9,149.342
Total Price: ₹ 59,979.022
Antigen
alpha-2-Macroglobulin
Classification
Polyclonal
Conjugate
Biotin
Gene
A2M
Gene Alias
A2m; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; Mam; S863 7; S863-7
Host Species
Goat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Accession No.
P01023
Gene Symbols
A2M
Immunogen
alpha-2-MACROGLOBULIN [Human Plasma]
Regulatory Status
RUO
Gene ID (Entrez)
2
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
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Description
- Store vial at 4°C prior to restoration
- For extended storage aliquot contents and freeze at -20°C or below
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-Alpha-2-Macroglobulin is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin and anti-Goat Serum as well as purified and partially purified alpha-2-MACROGLOBULIN [Human Plasma]
- Cross reactivity against alpha-2-MACROGLOBULIN from other sources is unknown
- Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits
- aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands
- This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma
- Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor
- In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.