AKT Monoclonal Antibody (14E5.16C8.25F6), Rockland™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-0532-Each-of-1 | In Stock | ₹ 14,952.00 |
50-199-0532 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,952.00
GST (18%): ₹ 2,691.36
Total Price: ₹ 17,643.36
Antigen
AKT
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P31749, P31750, P31751, P47196, P47197, Q60823, Q63484, Q9WUA6, Q9Y243
Gene Symbols
AKT1, Akt2, Akt3
Immunogen
Anti-AKT Antibody was produced by repeated immunizations in mice with a synthetic peptide corresponding to residues internal to the human AKT1 protein.
Regulatory Status
RUO
Gene ID (Entrez)
10000, 100609583, 11651, 11652, 207, 208, 23797, 24185, 25233, 29414, 456035, 740898
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
14E5.16C8.25F6
Conjugate
Unconjugated
Gene
AKT1
Gene Alias
2410016A19Rik; AI851531; Akt; Akt kinase; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT serine/threonine kinase 3; AKT/PKB; Akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; AKT2; AKT2 kinase; Akt3; AKT3 kinase; akt3a; AW554154; cb945; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; D930002M15Rik; DAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; dAkt1; DAKT1/PKB; DKFZp434N0250; Dmel\CG4006; Dmel_CG4006; Dpkb; DRAC-PK; DRAC-PK66; DRAC-PK85; HIHGHH; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; MPPH; MPPH2; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 1; murine thymoma viral (v-akt) oncogene homolog 2; Nmf350; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/Akt; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBB; PKBbeta; PKBG; PKB-GAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B a
Host Species
Mouse
Quantity
25 μL
Primary or Secondary
Primary
Target Species
Chimpanzee, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
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Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is specific for human and mouse AKT protein
- A BLAST analysis was used to suggest cross-reactivity with AKT1, AKT2, and AKT3 from human, mouse, rat and chimpanzee sources based on 100% homology with the immunizing sequence
- Cross-reactivity with AKT1, 2, 3 was determined with Western Blot
- Cross reactivity of AKT from other sources has not been determined
- AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins
- This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors
- Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9
- The AKT pathway is a major target for cancer drug discovery.