IL-6 Monoclonal Antibody (33A12.G9), Rockland™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1345-Each-of-1 | In Stock | ₹ 14,952.00 |
50-199-1345 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,952.00
GST (18%): ₹ 2,691.36
Total Price: ₹ 17,643.36
Antigen
IL-6
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P05231
Gene Symbols
Il6
Immunogen
This Protein A purified IL-6 monoclonal antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-6 produced in E.coli followed by hybridoma development.
Regulatory Status
RUO
Gene ID (Entrez)
3569
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Flow Cytometry, Western Blot
Clone
33A12.G9
Conjugate
Unconjugated
Gene
Il6
Gene Alias
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6
Host Species
Mouse
Quantity
25 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This purified antibody detects recombinant and native IL-6 present in body fluids and cell supernatants in various assays (ie
- IL-1 stimulated IL-6 production from fibroblasts)
- In Western blot analysis of natural cell products or human body fluids, multiple bands of IL-6 will appear due to the variable amount of glycosylation on the molecule
- Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells
- IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response
- IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells
- IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes
- In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes
- IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors
- IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma
- IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas
- Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha
- The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.