Phospho-RON (Tyr1360) Polyclonal Antibody, Rockland™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2044-Each-of-1 | In Stock | ₹ 52,930.08 |
50-199-2044 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
Phospho-RON (Tyr1360)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MST1R
Gene Alias
CD136; CDw136; c-met-related tyrosine kinase; friend virus susceptibility 2; Fv2; Fv-2; macrophage stimulating 1 receptor; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); Macrophage-stimulating protein receptor; Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain; MSP receptor; Mst1r; MST1R variant RON30; MST1R variant RON62; p185-Ron; protein tyrosine kinase 8; Protein-tyrosine kinase 8; PTK8; PTK8 protein tyrosine kinase 8; receptor protein tyrosine kinase, c-met-related; RON; RON variant E2E3; Stem cell-derived tyrosine kinase; Stk
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
4486
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
0.79 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
Q04912
Gene Symbols
MST1R
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum
- This antibody is specific for human RON protein phosphorylated at Y1360
- Cross-reactivity against RON from other species may occur but has not yet been tested
- Macrophage-stimulatin 1 receptor (MST1R/Ron), a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival
- The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits
- Ligand binding results in tyrosine phosphorylation of the beta chain
- In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period
- The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers
- MST1R/Ron expression has been documented in many normal human tissues
- ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uteru.