50-199-3832

HDAC4 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™

Manufacturer: Active Motif

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3832-Each-of-1 In Stock ₹ 53,560.20

50-199-3832 - Each of 1

₹ 53,560.20

In Stock

Quantity

1

Base Price: ₹ 53,560.20

GST (18%): ₹ 9,640.836

Total Price: ₹ 63,201.036

Antigen

HDAC4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HDAC4

Gene Alias

4932408F19Rik; AHO3; AI047285; BDMR; DKFZp779K1053; HA6116; HD4; HD7; HD7b; HD9; HDAC; Hdac4; HDAC-4; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDACA; HDAC-A; HDRP; Histone deacetylase 4; histone deacetylase A; KIAA0288; KIAA0744; MITR

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

208727, 9759

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Concentration

Lot-Specific

Formulation

PBS with 0.02% sodium azide; pH 7.5

Gene Accession No.

P56524, Q6NZM9

Gene Symbols

HDAC4

Immunogen

This HDAC4 antibody was raised against a synthetic peptide corresponding to amino acid residues 194-209 of human HDAC4.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4)
  • Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events
  • Histone deacetylases act via the formation of large multiprotein complexes
  • HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D
  • It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer
  • Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).