Estrogen Receptor alpha Mouse anti-Human, Clone: F3, Active Motif™
Manufacturer: Active Motif
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-3843-Each-of-1 | In Stock | ₹ 53,560.20 |
50-199-3843 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,560.20
GST (18%): ₹ 9,640.836
Total Price: ₹ 63,201.036
Antigen
Estrogen Receptor alpha
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.
P03372
Gene Symbols
ESR1
Immunogen
This ER-alpha antibody was raised against a peptide within the C-terminal region of human Estrogen Receptor alpha.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ChIP Assay, Western Blot
Clone
F3
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
BOS_9943; DKFZp686N23123; ER; Er alpha; ER36; Era; ERalpha; ER-alpha; ESR; Esr1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor alpha-like; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; LOC100351261; NR3A1; nuclear receptor; Nuclear re
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2099
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.