IL-5 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8559-Each-of-1 | In Stock | ₹ 1,75,552.50 |
50-271-8559 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,75,552.50
GST (18%): ₹ 31,599.45
Total Price: ₹ 2,07,151.95
Antigen
IL-5
Classification
Polyclonal
Conjugate
Biotin
Gene
Il5
Gene Alias
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3567
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P05113
Gene Symbols
Il5
Immunogen
E.coli-derived Recombinant Human IL-5
Quantity
500μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
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Description
- AA Sequence of recombinant protein: MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-5
- Anti-Human IL-5-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human IL-5 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IL-5 (500-P25) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IL-5
- Western Blot: To detect Human IL-5 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human IL-5 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P25BT-1MG will be provided as 2 x 500 μg IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils
- IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation
- The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes
- The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF)
- IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5
- IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.