50-559-906

CHOP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-559-906-Each-of-1 In Stock ₹ 44,150.23

50-559-906 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

CHOP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDIT3

Gene Alias

CEBPZ, CHOP, CHOP 10, DDIT 3, DDIT3, GADD153

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13198, 1649, 29467

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.37 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P35638, P35639, Q62857

Gene Symbols

DDIT3

Immunogen

CHOP Fusion Protein Ag7354

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta
  • Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites
  • Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets
  • Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress
  • Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.