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500P2401MG

TL1A Polyclonal Antibody, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 500P2401MG-Each-of-1 In Stock ₹ 1,75,686.00

500P2401MG - Each of 1

₹ 1,75,686.00

In Stock

Quantity

1

Base Price: ₹ 1,75,686.00

GST (18%): ₹ 31,623.48

Total Price: ₹ 2,07,309.48

Antigen

TL1A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFSF15

Gene Alias

bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15); MGC129934; MGC129935; TL1; TL1A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; TNFSF15; TNLG1B; tumor necrosis factor (ligand) superfamily member 15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand 1B; tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form; tumor necrosis factor superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor; vascular endothelial growth inhibitor-192A; Vegi; VEGI192A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9966

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O95150

Gene Symbols

TNFSF15

Immunogen

E.coli-derived Recombinant Human TL-1A

Quantity

1 mg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Description

  • AA Sequence of recombinant protein: QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human TL-1A
  • Anti-Human TL-1A-specific antibody was purified by affinity chromatography employing an immobilized Human TL-1A matrix
  • Sandwich ELISA: To detect Human TL-1A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human TL-1A (500-P240Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human TL-1A
  • Western Blot: To detect Human TL-1A by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human TL-1A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
  • This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells
  • The expression of this protein is inducible by TNF and IL-1 alpha
  • This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6
  • It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells
  • This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor
  • An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.