CD124 Recombinant Rabbit Monoclonal Antibody (Astra-1), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-124-182-Each-of-1 | In Stock | ₹ 34,265.00 |
53-124-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,265.00
GST (18%): ₹ 6,167.70
Total Price: ₹ 40,432.70
Antigen
CD124
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS, proprietary buffer with 0.09% sodium azide, pH 7.2
Gene Accession No.
P16382
Gene Symbols
Il4ra
Immunogen
Protein corresponding to mouse CD124 (aa26-aa233)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry
Clone
Astra-1
Conjugate
Alexa Fluor 488
Gene
Il4ra
Gene Alias
582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16190
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
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Description
- Description: This Astra-1 recombinant rabbit monoclonal antibody reacts with mouse CD124, which is also known as the IL4 receptor alpha (IL4RA) chain
- Applications Tested: This Astra-1 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.06 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser Filtration: 0.2 μm post-manufacturing filtered
- IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation
- The IL4 response is involved in promoting Th2 differentiation
- The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells
- It has no signaling abilities
- Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.