5323454

Progesterone R/NR3C3 Antibody (PR484) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Progesterone R/NR3C3

Concentration

1.0 mg/mL

Applications

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Breast Cancer, Cancer

Formulation

10mM PBS - BSA free with No Preservative

Gene ID (Entrez)

5241

Immunogen

A progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Clone

PR484

Dilution

Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, CyTOF-ready

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor

Gene Symbols

PGR

Isotype

IgG1 κ

Purification Method

Protein G purified

Test Specificity

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.

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Description

  • Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples
  • It is validated for Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.