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5350621

MilliporeSigma™ anti-F4/80 FITC, Clone: BM8.1,

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

F4/80

Applications

Flow Cytometry

Conjugate

FITC

Host Species

Rat

Research Discipline

Inflammation, Immunology

Formulation

Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.

Gene Symbols

Emr1, Gpf480

Primary or Secondary

Primary

Content And Storage

2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze

Clone

BM8.1

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Mouse

Gene Accession No.

Q61549

Immunogen

Proprietary immunogen

Purification Method

Purified by size-exclusion chromatography

Description

  • Specifically detects F4/80 Clone: BM8.1 in Mouse samples, and it is validated for Flow Cytometry The BM8.1 antibody is specific for mouse F4/80 antigen, a 125kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells
  • F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment
  • Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets
  • BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry.