beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)), Novus Biologicals™

beta 2-Microglobulin

0.2 mg/mL

Flow Cytometry, SDS-Page, Immunofluorescence

Unconjugated

Mouse

Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

B2M

IgG2a κ

Protein A or G purified

Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.

246-E9.E7 (same as HLA.ABC.m2)

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

Human, Primate (Negative)

P61769

567

Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.

Primary

Store at 4C.

12 kDa