5540761

HPV16 Antibody (SPM405), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

HPV16

Concentration

0.2 mg/mL

Applications

Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Virus

Gene Alias

Human Papilloma Virus Type 16

Isotype

IgG2a κ

Purification Method

Protein A or G purified

Test Specificity

Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

Clone

SPM405

Dilution

Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Immunogen

Recombinant major capsid protein L1 from human papilloma virus type 16

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

57 kDa

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Description

  • Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence HPV16 Monoclonal specifically detects HPV16 in Virus samples
  • It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.