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56-071-182

CD71 (Transferrin Receptor) Monoclonal Antibody (R17217 (RI7 217.1.4)), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Manufacturer: eBioscience

Select a Size

Pack Size SKU Availability Price
Each of 1 56-071-182-Each-of-1 In Stock ₹ 33,642.00

56-071-182 - Each of 1

₹ 33,642.00

In Stock

Quantity

1

Base Price: ₹ 33,642.00

GST (18%): ₹ 6,055.56

Total Price: ₹ 39,697.56

Antigen

CD71 (Transferrin Receptor)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q62351

Gene Symbols

TFRC

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22042

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

R17217 (RI7 217.1.4)

Conjugate

Alexa Fluor 700

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Rat

Quantity

100μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

  • Description: The R17217 monoclonal antibody reacts with mouse CD71, a 170-180 kDa type II transmembrane protein
  • CD71, the transferrin receptor, exists as a homodimer on the cell surface and is essential for cellular growth
  • CD71 is expressed by immature proliferating cells and at low levels on resting mature lymphocytes
  • Antigen or mitogen stimulation of T and B cells upregulates the expression of CD71
  • Expression level differences have been observed in different mouse strains
  • Applications Reported: This R17217 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This R17217 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
  • This may be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633-647 nm)
  • Most instruments will require a 685 LP mirror and 710/20 band pass filter
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.