CD144 (VE-cadherin) Monoclonal Antibody (16B1), Alexa Fluor™ 700, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-144-942-Each-of-1 | In Stock | ₹ 33,998.00 |
56-144-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,998.00
GST (18%): ₹ 6,119.64
Total Price: ₹ 40,117.64
Antigen
CD144 (VE-cadherin)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P33151
Gene Symbols
CDH5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1003
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
16B1
Conjugate
Alexa Fluor 700
Gene
CDH5
Gene Alias
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Description: The 16B1 antibody reacts with human CD144, also known as VE-cadherin and cadherin-5
- The cadherin family of receptors, which are calcium-dependent adhesion molecules, is known to be involved in homophilic cell interactions
- VE-cadherin, which is 140 kDa, is localized at the intercellular boundaries of endothelial cells in blood and lymphatic vessels in several tissues
- It is thought to play a role in vascular permeability and remodeling
- Applications Reported: This 16B1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 16B1 antibody has been pre-diluted and tested by flow cytometric analysis of Human Umbilical Vein Endothelial Cells (HUVEC)
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633-647 nm)
- Most instruments will require a 685 LP mirror and 710/20 band pass filter
- Please make sure that your instrument is capable of detecting this fluorochrome
- Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer
- VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
- Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions
- An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.