62-039-180
CD39 Monoclonal Antibody (24DMS1), Super Bright™ 436, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 62-039-180-Each-of-1 | In Stock | ₹ 16,287.00 |
62-039-180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,287.00
GST (18%): ₹ 2,931.66
Total Price: ₹ 19,218.66
Antigen
CD39
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P55772
Gene Symbols
ENTPD1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12495
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
24DMS1
Conjugate
Super Bright 436
Gene
ENTPD1
Gene Alias
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI
- E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP
- CD39 is the domit member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation
- CD39 can impact expression of CD73, another E-NTPase
- Together, these molecules influence inflammation responses
- CD39 is expressed on B cells, Langerhans cells and most monocytes
- In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells
- T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo
- Applications Reported: This 24DMS1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 24DMS1 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm
- CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes
- CD39 has intrinsic ecto-ATPase activity
- Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.