62-122-282

CD122 Monoclonal Antibody (TM-b1 (TM-beta1)), Super Bright™ 436, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 62-122-282-Each-of-1 In Stock ₹ 35,422.00

62-122-282 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD122

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P16297

Gene Symbols

Il2rb

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16185

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

TM-b1 (TM-beta1)

Conjugate

Super Bright 436

Gene

Il2rb

Gene Alias

CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Rat Monoclonal Antibody CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms
  • The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction
  • The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer
  • Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122
  • The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein
  • Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.