62-992-482
TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright™ 436, eBioscience™, Invitrogen™
Manufacturer: eBioscience
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 62-992-482-Each-of-1 | In Stock | ₹ 38,448.00 |
62-992-482 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,448.00
GST (18%): ₹ 6,920.64
Total Price: ₹ 45,368.64
Antigen
TLR4/MD-2 Complex
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9JHF9, Q9QUK6
Gene Symbols
Ly96, Tlr4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17087, 21898
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MTS510
Conjugate
Super Bright 436
Gene
Tlr4
Gene Alias
ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
Host Species
Rat
Quantity
100μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- The MTS510 monoclonal antibody reacts with the mouse Toll-like receptor 4 (TLR4)/MD-2 complex
- At least ten members of the Toll family have been identified
- This family of type I transmembrane proteins is characterized by an extracellular domain with leuc MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs)
- TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses
- TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS
- The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.