Lambda light chain Monoclonal Antibody (1-155-2), Super Bright™ 436, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 62-999-042-Each-of-1 | In Stock | ₹ 34,322.85 |
62-999-042 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,322.85
GST (18%): ₹ 6,178.113
Total Price: ₹ 40,500.963
Antigen
Lambda light chain
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P01701, P0CG04
Gene Symbols
IGL, IGLC1, IGLV, IGLV1-51
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
28820, 3535, 3537, 3546
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1-155-2
Conjugate
Super Bright 436
Gene
IGLC1
Gene Alias
Bence Jones Protein, BJP, Clambda1, Ig lambda chain V-I region BL2, IgL, Igl@, IGLC, IGLC 1/2/3, IGLC1, Igl-C1, IGLL5, IGLV, IGLV@, immmunoglobulin lambda light chain variable region, Immunoglobulin L, immunoglobulin lambda chain complex, immunoglobulin lambda constant 1, immunoglobulin lambda constant 7, immunoglobulin lambda light chain, immunoglobulin lambda light chain constant region, immunoglobulin lambda light chain V-J region, immunoglobulin lambda variable cluster, Lambda LC, lambda-immunoglobulin, LOC100060608, Mcg Marker, Paraprotein
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The monoclonal antibody 1-155-2 recognizes the lambda light chain of human immunoglobulin
- Approximately 22-kDa, the Ig lambda chain is comprised of one variable and one constant region
- Two lambda chains together with the heavy chain comprise the whole Ig structure
- Expression of Ig lambda is typically found in less than half of B lymphocytes, and has been associated with neoplastic lymphomas
- Applications Reported: This 1-155-2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1-155-2 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm
- We recommend using a 450/50 bandpass filter, or equivalent
- Please make sure that your instrument is capable of detecting this fluorochrome
- When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No
- SB-4401) to minimize any non-specific polymer interactions
- Please refer to the datasheet for Super Bright Staining Buffer for more information
- Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa)
- Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region
- The ratio of kappa to lambda is 70:30
- Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas
- Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.