CD8b Monoclonal Antibody (eBioH35-17.2 (H35-17.2)), Super Bright™ 702, eBioscience™, Invitrogen™
Manufacturer: eBioscience
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 67-008-382-Each-of-1 | In Stock | ₹ 38,092.00 |
67-008-382 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,092.00
GST (18%): ₹ 6,856.56
Total Price: ₹ 44,948.56
Antigen
CD8b
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P10300
Gene Symbols
Cd8b1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12526
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBioH35-17.2 (H35-17.2)
Conjugate
Super Bright 702
Gene
Cd8b1
Gene Alias
CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8a; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; CD8B1; CD8beta; CD8BP; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3
Host Species
Rat
Quantity
100μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The eBioH35-17.2 monoclonal antibody reacts with the mouse CD8 beta molecule
- The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells
- CD8 binds to MHC class I and plays a role in T cell development and activation of mature T cells
- Applications Reported: This eBioH35-17.2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBioH35-17.2 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Super Bright 702 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 702 nm
- We recommend using a 710/50 bandpass filter
- Please make sure that your instrument is capable of detecting this fluorochrome
- When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No
- SB-4401) to minimize any non-specific polymer interactions
- The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system
- The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules
- The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain
- Both alpha and beta chains share significant homology to immunoglobulin variable light chains
- This gene encodes the CD8 beta chain isoforms
- Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described
- A pseudogene, also located on chromosome 2, has been identified.