CD49d (Integrin alpha 4) Monoclonal Antibody (9F10), Super Bright™ 702, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 67-049-942-Each-of-1 | In Stock | ₹ 33,909.00 |
67-049-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,909.00
GST (18%): ₹ 6,103.62
Total Price: ₹ 40,012.62
Antigen
CD49d (Integrin alpha 4)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P13612
Gene Symbols
ITGA4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3676
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
9F10
Conjugate
Super Bright 702
Gene
ITGA4
Gene Alias
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This CF1D12 monoclonal antibody reacts with human CD52, a cell surface glycoprotein expressed in the immune and reproductive systems
- CF1D12 is thought to recognize the carbohydrate region of CD52, not the protein core of the molecule
- Tissue-specific modifications of the glycan structure may alter epitope recognition in certain applications
- For example, this CF1D12 clone has been reported to recognize human sperm glycoforms of CD52 by western blot, but not by flow cytometry
- The immunogen used to generate this antibody was human CD52
- Applications Reported: This CF1D12 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This CF1D12 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Super Bright 702 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 702 nm
- We recommend using a 710/50 bandpass filter
- Please make sure that your instrument is capable of detecting this fluorochrome
- When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
- Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
- Alpha4 chain associates with either beta1 or beta7 chain
- It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
- These ligands included Madcam, VCAM, and fibronectin
- Madcam is known as the principal ligand for integrin alpha4beta7
- Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.