NBS1 Recombinant Rabbit Monoclonal Antibody (9H4L65), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-267-0-Each-of-1 | In Stock | ₹ 42,720.00 |
70-267-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,720.00
GST (18%): ₹ 7,689.60
Total Price: ₹ 50,409.60
Antigen
NBS1
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
O60934
Gene Symbols
NBN
Immunogen
Protein corresponding to human NBS1 (aa400-aa754)
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
9H4L65
Conjugate
Unconjugated
Gene
NBN
Gene Alias
AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4683
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This antibody is predicted to react with Monkey, Bovine, Horse, Sheep Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex
- This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.