DDX1 Recombinant Rabbit Monoclonal Antibody (13H24L5), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-314-1-Each-of-1 | In Stock | ₹ 52,688.00 |
70-314-1 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,688.00
GST (18%): ₹ 9,483.84
Total Price: ₹ 62,171.84
Antigen
DDX1
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q91VR5, Q92499
Gene Symbols
DDX1
Immunogen
Protein corresponding to human DDX1 [aa72-aa283]
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Clone
13H24L5
Conjugate
Unconjugated
Gene
DDX1
Gene Alias
AA409185; ATP-dependent RNA helicase DDX1; DBP-RB; Ddx1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD box polypeptide 1; DEAD box protein 1; DEAD box protein retinoblastoma; DEAD box-1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DEAD/H-box helicase 1; UKVH5d
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
104721, 1653
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Cat, Rat
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase
- It is able to unwind both RNA-RNA and RNA-DNA duplexes
- DDX1 possesses 5' single-stranded RNA overhand nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides
- DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-b-mediated transcriptional activation
- It also acts as a positive transcriptional regulator of cyclin CCND2 expression
- It binds to the cyclin CCND2 promoter region
- DDX1 is a component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double stranded RNA and plays a role in activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1.