7069147
IgD Monoclonal Antibody (11-26c (11-26)), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IgD
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Gene ID (Entrez)
380797
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Clone
11-26c (11-26)
Applications
Flow Cytometry
Conjugate
Biotin
Host Species
Rat
Target Species
Mouse
Gene Symbols
Ighd
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Ighd
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Description
- Description: The 11-26c monoclonal antibody reacts with the delta heavy chain of mouse IgD
- It does not react with other classes of mouse immunoglobulin including IgA, IgG or IgM
- IgD is expressed by peripheral mature B cells
- 11-26c does not activate B cells
- Applications Reported: The 11-26c (11-26) antibody has been reported for use in flow cytometric analysis to detect the surface IgD on mouse B cells
- Applications Tested: The 11-26c (11-26) antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Filtration: 0.2 μm post-manufacturing filtered
- This type I transmembrane protein is co-expressed on the surface of mature naive B cells with membrane IgM
- IgD also exists as a soluble form in blood serum
- Studies have demonstrated that IgD associates with the B cell receptor and participates in mediating signal transduction upon antigen binding.