Perilipin-2/ADFP Antibody (ADFP/1494), Novus Biologicals™

Perilipin-2/ADFP

0.2 mg/mL

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Unconjugated

Mouse

Cancer, Hypoxia, Lipid and Metabolism, Lipid Droplets, Signal Transduction

10mM PBS with 0.05% BSA with 0.05% Sodium Azide

123

Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

48 kDa

ADFP/1494

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin 2-4 ug/ml, Immunofluorescence 0.5-1.0 ug/ml

Monoclonal

Purified

RUO

Human

ADFP, Adipophilin, Adipose differentiation-related proteinadipophilin, ADRP, MGC10598, perilipin 2, perilipin-2

PLIN2

IgG2b κ

Protein A or G purified

Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.