7092465
CD2 Mouse anti-Human, PE, Clone: RPA-2.10, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD2
Applications
Flow Cytometry
Conjugate
PE
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
RPA-2.10
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human Phytohemagglutinin-treated Lymphoblasts
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The RPA-2.10 monoclonal antibody specifically binds to CD2
- CD2 is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or the receptor for sheep erythrocytes
- CD2 belongs to the immunoglobulin superfamily of proteins along with its ligand LFA-3, CD58
- It is present on about 80-90% of human peripheral blood lymphocytes, greater than 95% of thymocytes, all T lymphocytes that form E-rosettes and a subset of NK cells
- CD2 plays a role in T-cell signaling and in lymphocyte adhesion
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.