7092691
CD86 Mouse anti-Human, APC, Clone: 2331 (FUN-1), BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD86
Applications
Flow Cytometry
Conjugate
APC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72
Clone
2331 (FUN-1)
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human HBL-1 Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells
- Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Cat
- No
- 555663) antibodies specifically recognize the same molecule, they react with different epitopes
- CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response
- The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies.