CD5 Mouse, Clone: CRIS-1, Novus Biologicals™

CD5

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page

Monoclonal

Purified

RUO

Human, Primate

P06127

921

Stimulated human leukocytes

Primary

Store at 4C.

67 kDa

CRIS-1

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)

Unconjugated

Mouse

Adaptive Immunity, Cell Biology, Cytokine Research, Immunology, Phospho Specific

PBS with 0.05% BSA. with 0.05% Sodium Azide

CD5 antigen, CD5 antigen (p56-62), CD5 molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, T1

CD5

IgG2a κ

Protein A purified

Recognizes a 67kDa transmembrane protein, which is identified as CD5 (HLDA I; WS Code T 29HLDA III; WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (∼10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.