ErbB2/Her2 Antibody (HRB2/718), Novus Biologicals™

ErbB2/Her2

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml

Monoclonal

Purified

RUO

Human

P04626

2064

Recombinant extracellular domain of human HER-2 protein

Primary

Store at 4C.

185 kDa

HRB2/718

Flow Cytometry, Immunocytochemistry, Immunofluorescence

Unconjugated

Mouse

Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Phospho Specific, Protein Kinase, Stem Cell Markers, Tumor Suppressors

PBS with 0.05% BSA. with 0.05% Sodium Azide

CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)

ERBB2

IgG1 κ

Protein A purified

Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.