Insulin Mouse, Clone: SPM139, Novus Biologicals™

Insulin

Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Monoclonal

Purified

RUO

Human, Porcine, Bovine, Mouse (Negative), Rat (Negative)

P01308

3630

Full length (1-84 amino acid) purified pig insulin, conjugated to KLH

Primary

Store at 4C.

6 kDa

SPM139

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Unconjugated

Mouse

Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

PBS with 0.05% BSA. with 0.05% Sodium Azide

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

INS

IgG1 κ

Protein A purified

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.