VCAM-1/CD106 Antibody (B-K9) - Azide and BSA Free, Novus Biologicals™

VCAM-1/CD106

1.0 mg/mL

Flow Cytometry, Immunofluorescence, CyTOF

Unconjugated

Mouse

Cancer, Mesenchymal Stem Cell Markers, Stem Cell Markers

PBS with No Preservative

7412

Activated human umbilical vein endothelial cells (HUVEC)

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

110 kDa

B-K9

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Monoclonal

Purified

RUO

Human

CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

VCAM1

IgG1 κ

Protein A or G purified

Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.