Arginase 1/ARG1/liver Arginase Antibody (ARG1/1126) - Azide and BSA Free, Novus Biologicals™

Arginase 1/ARG1/liver Arginase

1.0 mg/mL

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Unconjugated

Mouse

Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism, Myeloid derived Suppressor Cell

PBS with No Preservative

383

Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

36.5 kDa

ARG1/1126

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Monoclonal

Purified

RUO

Human

arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

ARG1

IgG3 κ

Protein A or G purified

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.