7106007

ErbB2/Her2 Antibody (4D5-8 (trastuzumab)) - Chimeric - Azide and BSA Free, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

ErbB2/Her2

Dilution

Flow Cytometry 1:10 - 1:1000, ELISA 1:100 - 1:2000, Immunohistochemistry 1:10 - 1:500, CyTOF-ready

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)

Gene Symbols

ERBB2

Isotype

IgG

Purification Method

Protein A or G purified

Test Specificity

Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.

Clone

4D5-8 (trastuzumab)

Applications

Flow Cytometry, ELISA, Immunohistochemistry, CyTOF

Conjugate

Unconjugated

Host Species

Rabbit

Research Discipline

Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Oncogenes, Protein Kinase, Stem Cell Markers, Tumor Suppressors

Formulation

PBS with 0.02% Proclin 300. with 0.02% Proclin 300

Gene ID (Entrez)

2064

Immunogen

A431 cells (human epidermoid carcinoma) (over)expressing EGFR.

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Description

  • ErbB2/Her2 Monoclonal specifically detects ErbB2/Her2 in Human samples
  • It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.